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KMID : 0380620100420050571
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Korean Journal of Food Science and Technology
2010 Volume.42 No. 5 p.571 ~ p.577
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Antioxidant Activity and Anti-hyperglycemic Activity of Medicinal Herbal Extracts According to Extraction Methods
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Jeong Hyun-Jin
Lee Sung-Kyu
Lee Eun-Ju
Park Woo-Dong
Kim Jong-Boo
Kim Hyun-Jeong
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Abstract
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Korean traditional medicinal herbs have been reported to possess antioxidant and anti-hyperglycemic activities. We tested the antioxidant and anti-hyperglycemic activities of 6 kinds of medicinal herbs: Angelica gigas N., Poria cocos, Mori radicis Cortex, Mori folium, Aralia elata Cortex, and Panax ginseng, prepared as hot water, ethanol, and sonication extracts. The antioxidant activities of the extracts were examined by performing total polyphenol, total flavonoid, and α,α-diphenyl-β-picrylhydrazyl (DPPH) assays. For M. folium, the ethanol extract showed the strongest effects in DPPH radical scavenging activity among the three extraction methods. In addition, sonication extracts of M. radicis Cortex and M. folium showed the highest inhibitory activities for α-glucosidase among the different extracts. The ethanol extracts of M. folium had the highest inhibition effects against α-amylase. A direct correlation between antioxidant and anti-hyperglycemic inhibition activity was found in the ethanol and sonication extracts. From the results, it is considered that these six medicinal herbal extracts have antioxidative, anti-hyperglycemic, and correlation effects based on different extraction methods.
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KEYWORD
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medicinal plants, antioxidant, anti-hyperglycemic, hot water extracts, ethanol extracts, sonication extracts
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